Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179481 | 0.81 | KDM5B (0.33) | ALDH1A1HTTSMN1; SMN2L3MBTL1SLC22A12 | |
| SCHEMBL17018460 | 0.79 | ALDH1A1 (0.34) | ALDH1A1HTTSMN1; SMN2L3MBTL1RORC | |
| SCHEMBL19815546 | 0.77 | PIK3CD (0.33) | ALDH1A1HTTSMN1; SMN2L3MBTL1PIK3CD | |
| SCHEMBL19135627 | 0.77 | ALDH1A1 (0.31) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2611113 | 0.76 | NPBWR1 (0.41) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL21863672 | 0.74 | ALDH1A1 (0.33) | ALDH1A1HTTSMN1; SMN2L3MBTL1RORC | |
| SCHEMBL19176085 | 0.74 | JAK2 (0.35) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL21536772 | 0.74 | ALOX5AP (0.33) | — | |
| SCHEMBL24861815 | 0.74 | JAK2 (0.33) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15038278 | 0.74 | FDPS (0.36) | ALDH1A1HTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015513-B1 | IRAK INHIBITOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI MEIYUE BIOTECH DEV CO LTD (CN) | 2023-11-01 | — | — | EP | disclosed |
| EP-4056568-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-09-14 | — | — | EP | disclosed |
| EP-4015513-A1 | IRAK INHIBITOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021057785-A1 | IRAK INHIBITOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2021-04-01 | — | — | WO | disclosed |