SCHEMBL2315537

SCHEMBL2315537

CSc1nc2nc(C)cc(O)n2n1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
KDM4E B2RXH2 5/20 0.57
HPGD P15428 5/20 0.57
HSD17B10 Q99714 2/20 0.57
CYP1A2 P05177 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.43
RECQL P46063 1/20 0.43
ALOX15 P16050 1/20 0.42
KDM1A O60341 1/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
ATM Q13315 1/20 0.40
CKS1B P61024 1/20 0.40
SKP2 Q13309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5688394 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL15707810 0.82 KDM4E (0.68) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL4612108 0.82 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL13140142 0.80 KDM4E (0.41) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL4613719 0.80 L3MBTL1 (0.46) ALDH1A1HPGDSMN1; SMN2RECQL
SCHEMBL1681653 0.79 KDM4E (0.57) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL9785934 0.78 RECQL (0.43) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL10623008 0.77 SMN1; SMN2 (0.57) ALDH1A1KDM4EHPGDCYP1A2SMN1; SMN2
SCHEMBL8520132 0.77 KDM1A (0.67) ALDH1A1KDM4EHPGDCYP1A2SMN1; SMN2
SCHEMBL13996431 0.77 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDCYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115352094-B Optical lens capable of preventing light pollution and preparation process thereof 久悦达昕科技(深圳)有限公司 2024-07-19 CN claimed
CN-115352094-A Optical lens capable of preventing light pollution and preparation process thereof 久悦达昕科技(深圳)有限公司 2022-11-18 CN claimed
WO-2006011797-A1 RECORDING MEDIA FUJI PHOTO FILM B.V. (NL) 2006-02-02 WO claimed
EP-1193543-B1 Black and white graphic arts film EASTMAN KODAK CO (US) 2005-05-25 EP claimed
US-6444392-B1 Black and white graphic arts film EASTMAN KODAK COMPANY 2002-09-03 US claimed
EP-1193543-A2 Black and white graphic arts film EASTMAN KODAK COMPANY (US) 2002-04-03 EP claimed
US-5232827-A Containing an ammonium salt; antifogging agents; storage stability EASTMAN KODAK COMPANY (US) 1993-08-03 US claimed
EP-0215612-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (5) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-02-24 EP claimed
EP-0233396-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (4) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 EP claimed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 US claimed
EP-0215612-A2 Silver halide photographic emulsions with novel grain faces (5) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-03-25 EP claimed
US-4643966-A SPECTRAL SENSITIZING DYES AS GROWTH MODIFIERS; ANTIFOGGING AGENTS, STABILIZERS; TETRAAZAINDENES, CARBOCYANINES EASTMAN KODAK COMPANY (US) 1987-02-17 US claimed
CN-115352094-B Optical lens capable of preventing light pollution and preparation process thereof 久悦达昕科技(深圳)有限公司 2024-07-19 CN disclosed
CN-115352094-A Optical lens capable of preventing light pollution and preparation process thereof 久悦达昕科技(深圳)有限公司 2022-11-18 CN disclosed
US-9963451-B2 Fused ring pyrimidine compound and pest control agent containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2018-05-08 US disclosed
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2015-12-24 US disclosed
US-4659647-A BLEND WITH HYDROPHOBIC POLYMER AND STABILIZER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-04-21 US disclosed
EP-0215612-A2 Silver halide photographic emulsions with novel grain faces (5) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-03-25 EP disclosed
US-4643966-A SPECTRAL SENSITIZING DYES AS GROWTH MODIFIERS; ANTIFOGGING AGENTS, STABILIZERS; TETRAAZAINDENES, CARBOCYANINES EASTMAN KODAK COMPANY (US) 1987-02-17 US disclosed
EP-0185243-A2 Photosensitive silver halide material for obtaining half-tone black-and-white images and method for half-tone high-contrast reproduction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-06-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368249-A1 FUSED RING PYRIMIDINE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME CBR3, HRH2, HRH4 ALDH1A1 3675/4885KDM4E 1972/4885HPGD 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.