SCHEMBL5688394

SCHEMBL5688394

CSc1nc2nc(C)cc(O)n2n1.[NaH]

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 5/20 0.56
HPGD P15428 5/20 0.56
HSD17B10 Q99714 2/20 0.56
CYP1A2 P05177 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.42
RECQL P46063 1/20 0.42
ALOX15 P16050 1/20 0.41
KDM1A O60341 1/20 0.40
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
ATM Q13315 1/20 0.39
CKS1B P61024 1/20 0.39
SKP2 Q13309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2315537 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL15707810 0.81 KDM4E (0.68) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL4612108 0.81 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL13140142 0.79 KDM4E (0.41) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL4613719 0.78 L3MBTL1 (0.46) ALDH1A1HPGDSMN1; SMN2RECQL
SCHEMBL1681653 0.78 KDM4E (0.57) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL9785934 0.77 RECQL (0.43) ALDH1A1KDM4EHPGDHSD17B10CYP1A2
SCHEMBL10623008 0.76 SMN1; SMN2 (0.57) ALDH1A1KDM4EHPGDCYP1A2SMN1; SMN2
SCHEMBL8520132 0.76 KDM1A (0.67) ALDH1A1KDM4EHPGDCYP1A2SMN1; SMN2
SCHEMBL13996431 0.76 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDCYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718679-B1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK CO (US) 2006-02-15 EP disclosed
EP-0772079-B1 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK CO (US) 2002-12-11 EP disclosed
US-5792601-A MODIFYING THE PERFORMANCE PROPERTIES OF THE HIGH CHLORIDE SILVER HALIDE EMULSION BY A COMBINATION OF SILVER BROMIDE ADDITION, IRIDIUM DOPANT INCORPORATION AND ANTIFOGGANT ADDITION EASTMAN KODAK COMPANY (US) 1998-08-11 US disclosed
US-5736310-A SILVER IODOCHLORIDE GRAINS GROWN IN DISPERSING MEDIUM; EMPLOYING GRAINS AS SUBSTRATES FOR FURTHER GRAIN GROWTH EASTMAN KODAK COMPANY (US) 1998-04-07 US disclosed
US-5728516-A Photographic print elements containing cubical grain silver iodochloride emulsions EASTMAN KODAK COMPANY (US) 1998-03-17 US disclosed
US-5726005-A Photographic print elements containing cubical grain silver iodochloride emulsions EASTMAN KODAK COMPANY (US) 1998-03-10 US disclosed
EP-0772079-A2 Light-sensitive silber halide emulsions and processes for their preparation EASTMAN KODAK COMPANY (US) 1997-05-07 EP disclosed
EP-0718679-A1 Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
EP-0718676-A1 Photographic print elements containing emulsions of enhanced speed and controlled minimum densities EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
EP-0617320-A2 Tabular grain emulsions containing antifoggants and stabilizers EASTMAN KODAK COMPANY (US) 1994-09-28 EP disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 US disclosed