Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23144126 | 0.83 | CA12 (0.45) | ADAM17BRD4CA1CA2CA9 | |
| SCHEMBL17146965 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ALDH3A1MAPT | |
| SCHEMBL6807006 | 0.73 | CA1 (0.44) | CA1CA2CA9ALDH1A1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL6511653 | 0.71 | CA1 (0.43) | CA1CA2CA9ALDH1A1ALDH3A1 | |
| SCHEMBL23144110 | 0.69 | PDK1 (0.46) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL758951 | 0.67 | LMNA (0.64) | ALDH1A1PKM | |
| SCHEMBL29212406 | 0.67 | CA12 (0.42) | ADAM17BRD4CA1CA2CA9 | |
| SCHEMBL23143891 | 0.67 | CA12 (0.49) | ADAM17CA1CA2CA5ACA7 | |
| SCHEMBL29812039 | 0.67 | CA12 (0.49) | ADAM17CA1CA2CA5ACA7 | |
| SCHEMBL24574571 | 0.66 | LMNA (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021061643-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-04-01 | — | — | WO | disclosed |