Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6511653 | 0.98 | CA1 (0.43) | CA1CA2CA9G6PDIDE | |
| SCHEMBL6810299 | 0.85 | CA2 (0.62) | CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6517794 | 0.83 | CA2 (0.61) | CA1CA2CA9 | |
| SCHEMBL11715144 | 0.83 | CA1 (0.43) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL17146965 | 0.82 | ALDH1A1 (0.42) | G6PDIDEALDH1A1ALDH3A1MAPT | |
| SCHEMBL9135441 | 0.81 | SMN1; SMN2 (0.50) | CA1CA2CA9G6PDIDE | |
| SCHEMBL9703261 | 0.79 | CA2 (0.71) | CA1CA2CA9ALDH1A1MAPT | |
| SCHEMBL1243294 | 0.79 | CA1 (0.71) | CA1CA2CA9G6PDIDE | |
| Hydrochloric Acid SCHEMBL6514091 | 0.78 | CA1 (0.69) | CA1CA2CA9G6PDIDE | |
| SCHEMBL6810896 | 0.77 | SMN1; SMN2 (0.54) | CA1CA2CA9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-B1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER (US) | 2004-05-19 | — | — | EP | claimed |