Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106098 | 0.84 | ACHE (0.50) | ACHECA12CA1CA2CA7 | |
| SCHEMBL6426051 | 0.77 | ACHE (0.42) | ACHECA12ALDH1A1CA1CA2 | |
| SCHEMBL4936785 | 0.75 | ACHE (0.67) | ACHECA12ALDH1A1CA1CA2 | |
| SCHEMBL20101128 | 0.75 | ENPP2 (0.48) | ACHECA12ALDH1A1CA1CA2 | |
| SCHEMBL13492226 | 0.74 | GPR84 (0.39) | ACHECA12ALDH1A1CA1CA2 | |
| SCHEMBL13224699 | 0.74 | ALDH1A1 (0.50) | ACHEALDH1A1TDP1HSP90AB1THRB | |
| SCHEMBL4780801 | 0.74 | ERN1 (0.36) | ACHETDP1HSP90AB1LTA4HCBS | |
| SCHEMBL13224583 | 0.74 | CA12 (0.50) | ACHECA12CA1CA9HSP90AB1 | |
| SCHEMBL25132436 | 0.73 | ACHE (0.44) | ACHECA12ALDH1A1CA1CA2 | |
| SCHEMBL15805541 | 0.73 | ACHE (0.39) | ACHECA12ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2529023-A1 | MICROORGANISM PRODUCTION OF HIGH-VALVE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | OPX Biotechnologies Inc. (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011094457-A1 | MICROORGANISM PRODUCTION OF HIGH-VALVE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | OPX BIOTECHNOLOGIES, INC. (US) | 2011-08-04 | — | — | WO | disclosed |