Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HTR3A | P46098 | 5/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.33 |
| ▸ | HTR3B | O95264 | 2/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161009 | 0.83 | KDM4E (0.38) | LCKHRH4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL23160983 | 0.83 | HRH4 (0.51) | HRH4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23161812 | 0.81 | LCK (0.37) | LCKHRH4HTR3AHTR3EHTR3B | |
| SCHEMBL23161881 | 0.78 | ALDH1A1 (0.49) | LCKSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL23160990 | 0.77 | POLR1A (0.37) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL23160995 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EGAAMAPTCASP1 | |
| SCHEMBL23161001 | 0.77 | SYK (0.37) | NPC1TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20078423 | 0.75 | HTR3A (0.50) | HRH4HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL23161883 | 0.74 | ALDH1A1 (0.44) | NPC1TP53RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18057406 | 0.72 | ALDH1A1 (0.36) | LCKHRH4NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094952-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | UNITED STATES GOVERNMENT | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094952-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | BAX, CASP3, BCL2 | LCK 2332/4885HRH4 4546/4885HTR3A 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.