Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335645 | 0.81 | ALDH1A1 (0.42) | ALDH1A1RAB9ASMN1; SMN2USP7CYP3A4 | |
| SCHEMBL17204603 | 0.75 | HCAR2 (0.50) | ALDH1A1RAB9ASMN1; SMN2USP7CYP3A4 | |
| SCHEMBL5875664 | 0.73 | RAB9A (0.47) | ALDH1A1RAB9ASMN1; SMN2USP7CYP3A4 | |
| SCHEMBL17204004 | 0.70 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2USP7NPC1 | |
| SCHEMBL854956 | 0.69 | — | — | |
| SCHEMBL4781387 | 0.69 | — | — | |
| SCHEMBL15553434 | 0.69 | — | — | |
| SCHEMBL4519703 | 0.67 | — | — | |
| SCHEMBL3208200 | 0.67 | — | — | |
| SCHEMBL2057950 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2025-07-22 | — | — | US | claimed |
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2024-02-15 | — | — | US | claimed |
| EP-4038056-B1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2023-11-08 | — | — | EP | claimed |
| CN-114555568-A | Preparation of 2-chloro-1- (2-chlorothiazol-5-yl) ethanone | 巴斯夫欧洲公司 | 2022-05-27 | — | — | CN | claimed |
| WO-2021063880-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2021-04-08 | — | — | WO | claimed |
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2025-07-22 | — | — | US | disclosed |
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2024-02-15 | — | — | US | disclosed |
| EP-4038056-B1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2023-11-08 | — | — | EP | disclosed |
| CN-114555568-A | Preparation of 2-chloro-1- (2-chlorothiazol-5-yl) ethanone | 巴斯夫欧洲公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021063880-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | CYP2J2, CLK2, CLK1 | ALDH1A1 316/4885RAB9A 3345/4885SMN1; SMN2 4089/4885 |
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | CYP2J2, CLK2, CLK1 | ALDH1A1 316/4885RAB9A 3345/4885SMN1; SMN2 4089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.