Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774496 | 0.82 | MAPT (0.55) | MAOBARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10710069 | 0.82 | MAPT (0.55) | MAOBARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2774494 | 0.82 | MAPT (0.55) | MAOBARGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2320609 | 0.79 | AMY1A (0.53) | MAOBKDM4EKMT2AGAAMAPT | |
| SCHEMBL17526396 | 0.79 | NFE2L2 (0.48) | MAOBGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18372473 | 0.79 | AMY1A (0.53) | MAOBKDM4EKMT2AGAAMAPT | |
| SCHEMBL8821791 | 0.78 | CA2 (0.55) | MAOBARCA9CA3CA6 | |
| SCHEMBL8821790 | 0.78 | CA2 (0.55) | MAOBARCA9CA3CA6 | |
| SCHEMBL31681674 | 0.77 | KDM1A (0.49) | KDM1AKDM4EKMT2AGAAMAPT | |
| SCHEMBL14906945 | 0.76 | CA12 (0.58) | MAOBCA9KDM1AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189306-A1 | COMPOUNDS, COMPOSITIONS AND TREATMENTS FOR V-ATPase RELATED DISEASES | KARTNER NORBERT | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189306-A1 | COMPOUNDS, COMPOSITIONS AND TREATMENTS FOR V-ATPase RELATED DISEASES | ATP6V1E1, ATP6V1G1, ATP6V1H | MAOB 917/4885AR 4775/4885GRIN2D 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.