Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.69 |
| ▸ | HTR2B | P41595 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | HTR1D | P28221 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | HTR1B | P28222 | 2/20 | 0.69 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.69 |
| ▸ | HTR3B | O95264 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | HTR1E | P28566 | 1/20 | 0.69 |
| ▸ | HTR1F | P30939 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788551 | 0.86 | HTR2C (0.75) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL28672341 | 0.85 | HTR2C (0.70) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL29471374 | 0.84 | HTR2C (1.00) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL1127784 | 0.84 | HTR2C (1.00) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL14297488 | 0.84 | HTR2C (0.73) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL29679229 | 0.82 | SPR (0.76) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL6028502 | 0.82 | SPR (0.67) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| SCHEMBL13645692 | 0.82 | SPR (0.76) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| Serotonin SCHEMBL1495 | 0.82 | HTR2C (1.00) | HTR2CCYP2D6KDM4EMEN1KMT2A | |
| Serotonin SCHEMBL30057954 | 0.82 | HTR2C (1.00) | HTR2CCYP2D6KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989968-A | Carbostyril derivatives and serotonin reuptake inhibitors for treatment of mood disorders | OTSUKA PHARMA CO LTD (JP) | 2007-07-04 | — | — | CN | claimed |
| CN-114410547-B | Lactobacillus pentosus LPQ1 capable of promoting 5-HTP secretion and relieving depression and application thereof | 西南大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-114410547-A | Lactobacillus pentosus LPQ1 capable of promoting secretion of 5-HTP and relieving depression and application thereof | 西南大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-105384676-B | Triple reuptaking inhibitors and its application method | 桑诺维恩药品公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-103025357-B | Selectively deliver compositions and the method for the most specific neural metaclass of oligonucleotide molecules | NLIFE THERAPEUTICS, S.L. (ES) | 2016-12-14 | — | — | CN | disclosed |
| US-20160032330-A1 | P-450-CATALYZED ENANTIOSELECTIVE CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-02-04 | — | — | US | disclosed |
| US-9075014-B2 | pH-responsive fluorescent false neurotransmitters and their use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130190497-A1 | FLUORESCENT SUBSTRATES FOR MONOAMINE TRANSPORTERS AS OPTICAL FALSE NEUROTRANSMITTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-07-25 | — | — | US | disclosed |
| CN-102286582-B | Method for preparing memory-improving bioactive peptide from deep sea fish | UNIV SOUTH CHINA TECH | 2013-07-24 | — | — | CN | disclosed |
| US-20130171664-A1 | PH-RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-07-04 | — | — | US | disclosed |
| US-20090311795-A1 | BILATERAL CONTROL OF FUNCTIONS TRADITIONALLY REGULATED BY ONLY SEROTONIN OR ONLY DOPAMINE | Vidas, Arrett & Steinkraus, P.A. | 2009-12-17 | — | — | US | disclosed |
| WO-2009152426-A1 | BILATERAL CONTROL OF FUNCTIONS TRADITIONALLY REGULATED BY ONLY SEROTONIN OR ONLY DOPAMINE | HINZ MARTIN (US) | 2009-12-17 | — | — | WO | disclosed |
| CN-101406469-A | Use of GAL3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods | LUNDBECK & CO AS H (DK) | 2009-04-15 | — | — | CN | disclosed |
| CN-100446767-C | Use of GAL3 receptor antagonists for the manufacture of a medicament for the treatment of depression and/or anxiety and compounds useful in such a method | SYNAPTIC PHARMA CORP (DK) | 2008-12-31 | — | — | CN | disclosed |
| WO-2008013997-A2 | FLUORESCENT SUBSTRATES FOR MONOAMINE TRANSPORTERS AS OPTICAL FALSE NEUROTRANSMITTERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-01-31 | — | — | WO | disclosed |
| CN-1499970-A | Use of GAL3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods | �����յٿ�ҩ������˾ | 2004-05-26 | — | — | CN | disclosed |
| WO-2001013715-A2 | ANIMAL MODEL AND USES THEREOF | THE BABRAHAM INSTITUTE (GB) | 2001-03-01 | — | — | WO | disclosed |
| US-5990094-A | SEROTONIN N-ACETYLTRANSFERASE INHIBITORS WHICH CAN SERVE AS BIOLOGICAL TOOLS THAT HELP REVEAL BIOLOGICAL FUNCTIONS FOR MELATONIN AND PINEAL SEROTONIN IN VIVO; ACETYL-COA N-ACETYL TRYPTAMINE DERIVATIVES OF GIVEN STRUCTURE | THE ROCKEFELLER UNIVERSITY (US) | 1999-11-23 | — | — | US | disclosed |
| US-4051186-A | AMINO-PROPRANOLOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-09-27 | — | — | US | disclosed |
| US-3950422-A | 6-Amino-isoproterenol | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190497-A1 | FLUORESCENT SUBSTRATES FOR MONOAMINE TRANSPORTERS AS OPTICAL FALSE NEUROTRANSMITTERS | SLC18A2, SLC6A2, SLC18A3 | HTR2C 185/4885CYP2D6 1088/4885KDM4E 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.