Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.76 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | IDO1 | P14902 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.69 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679229 | 1.00 | SPR (0.76) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| SCHEMBL1960963 | 0.87 | SPR (0.78) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| Acetylserotonin SCHEMBL30295379 | 0.86 | SPR (1.00) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| Acetylserotonin SCHEMBL422165 | 0.86 | SPR (1.00) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| Acetylserotonin SCHEMBL29375184 | 0.86 | SPR (1.00) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| SCHEMBL6028502 | 0.86 | SPR (0.67) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| SCHEMBL25137286 | 0.85 | TRPV1 (0.76) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| SCHEMBL625920 | 0.85 | MTNR1A (0.76) | NOTUMHPGDMTNR1AMTNR1BPTGS1 | |
| Acetylserotonin SCHEMBL31488730 | 0.85 | SPR (0.97) | SPRKDM4ECYP2D6NPSR1NOTUM | |
| Acetylserotonin SCHEMBL29669245 | 0.85 | SPR (0.97) | SPRKDM4ECYP2D6NPSR1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210023052-A1 | COMPOSITIONS CONTAINING TOAD SECRETION COMPOUNDS | CAAMTECH, INC. | 2021-01-28 | — | — | US | disclosed |
| US-9486441-B2 | Compounds, compositions and methods for making the same | SIGNUM BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| WO-2009132051-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | SIGNUM BIOSCIENCES, INC. | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264496-A1 | Compounds, Compositions and Methods for Making the Same | PPP2CA, PPP4C, PPP6C | SPR 1640/4885KDM4E 243/4885CYP2D6 3523/4885 |
| US-20210023052-A1 | COMPOSITIONS CONTAINING TOAD SECRETION COMPOUNDS | HTR5A, HTR1A, HTR7 | SPR 1988/4885KDM4E 2132/4885CYP2D6 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.