Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516745 | 0.80 | MAPK1 (0.69) | MAPK1TSHRLMNAPOLBPDE7A | |
| SCHEMBL31903 | 0.80 | HSD17B10 (0.50) | TSHRHSD11B1ALDH1A1S100A4TRPV1 | |
| SCHEMBL23167082 | 0.79 | MAPK1 (0.47) | MAPK1TSHRHSD11B1LMNAPOLB | |
| SCHEMBL23166960 | 0.78 | MAPK1 (0.53) | MAPK1TSHRLMNAPOLBPDE7A | |
| SCHEMBL1459853 | 0.77 | MAPT (0.56) | TSHRALDH1A1S100A4TRPV1MAPT | |
| SCHEMBL31005993 | 0.77 | MAPT (0.56) | TSHRALDH1A1S100A4TRPV1MAPT | |
| SCHEMBL17727815 | 0.77 | HSD11B1 (0.59) | MAPK1TSHRHSD11B1PDE7APDE7B | |
| SCHEMBL26205134 | 0.77 | S100A4 (0.56) | MAPK1TSHRALDH1A1S100A4TRPV1 | |
| SCHEMBL23167170 | 0.77 | S100A4 (0.44) | MAPK1TSHRHSD11B1S100A4TRPV1 | |
| SCHEMBL29966820 | 0.77 | S100A4 (0.44) | MAPK1TSHRHSD11B1S100A4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12384760-B2 | Substituted carbazole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-08-12 | — | — | US | disclosed |
| CN-114829350-B | Substituted carbazole compounds | 百时美施贵宝公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20240076280-A1 | SUBSTITUTED CARBAZOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2024-03-07 | — | — | US | disclosed |
| EP-4038059-B1 | SUBSTITUTED CARBAZOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-20 | — | — | EP | disclosed |
| EP-4038059-B1 | SUBSTITUTED CARBAZOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-20 | — | — | EP | disclosed |
| EP-4038059-A1 | SUBSTITUTED CARBAZOLE COMPOUNDS | Bristol-Myers Squibb Company (US) | 2022-08-10 | — | — | EP | disclosed |
| CN-114829350-A | Substituted carbazole compounds | 百时美施贵宝公司 | 2022-07-29 | — | — | CN | disclosed |
| WO-2021067657-A1 | SUBSTITUTED CARBAZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021067657-A1 | SUBSTITUTED CARBAZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240076280-A1 | SUBSTITUTED CARBAZOLE COMPOUNDS | TLR7, TLR3, TLR1 | MAPK1 519/4885TSHR 530/4885HSD11B1 3568/4885 |
| US-12384760-B2 | Substituted carbazole compounds | TLR7, TLR3, TLR1 | MAPK1 519/4885TSHR 530/4885HSD11B1 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.