SCHEMBL17727815

SCHEMBL17727815

Cc1cc(Cl)ccc1-c1ccccc1[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.59
▸ HSD17B10 Q99714 1/20 0.50
▸ MAPK1 P28482 2/20 0.47
▸ TSHR P16473 2/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ MAPT P10636 2/20 0.46
▸ HPGD P15428 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ PDE7A Q13946 2/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ PDE7B Q9NP56 1/20 0.44
▸ NPBWR1 P48145 1/20 0.44
▸ MAOB P27338 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ KIF18A Q8NI77 1/20 0.43
▸ EIF4E P06730 3/20 0.43
▸ GSK3B P49841 1/20 0.43
▸ NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31542121 0.83 MAOB (0.56) HSD11B1HSD17B10MAPK1TSHRTDP1
SCHEMBL1558206 0.83 HSD11B1 (0.66) HSD11B1MAPK1TSHRTDP1ALDH1A1
SCHEMBL27986193 0.83 NPBWR1 (0.55) HSD11B1HSD17B10MAPK1TSHRTDP1
SCHEMBL2360248 0.81 HSD17B10 (0.69) HSD17B10MAPK1TSHRTDP1ALDH1A1
SCHEMBL30564320 0.81 HSD17B10 (0.69) HSD17B10MAPK1TSHRTDP1ALDH1A1
SCHEMBL31903 0.81 HSD17B10 (0.50) HSD11B1HSD17B10TSHRTDP1ALDH1A1
SCHEMBL29829608 0.81 HSD11B1 (0.52) HSD11B1MAPK1TSHRTDP1ALDH1A1
SCHEMBL8158755 0.79 HSD17B10 (0.49) HSD11B1HSD17B10TSHRTDP1ALDH1A1
SCHEMBL23167300 0.77 MAPK1 (0.47) HSD11B1MAPK1TSHRTDP1ALDH1A1
SCHEMBL359844 0.77 TSHR (0.64) HSD17B10MAPK1TSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12615957-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-04-28 — — US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 — — US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 — — US disclosed
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 — — US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 — — US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 — — US disclosed
US-11832507-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 — — US disclosed
US-20210280803-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-09 — — US disclosed
US-20210280803-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-09 — — US disclosed
US-11043641-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-22 — — US disclosed
US-10038151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-31 — — US disclosed
US-10038151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-31 — — US disclosed
US-10038151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-31 — — US disclosed
CN-105585594-A Organic electroluminescent materials and devices, and mixed materials UNIVERSAL DISPLAY CORP 2016-05-18 — — CN disclosed
US-20160133859-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-12 — — US disclosed
US-20160133859-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-12 — — US disclosed
US-20160133860-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-12 — — US disclosed
US-20160133859-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-12 — — US disclosed
US-20160133860-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-12 — — US disclosed
US-20160133860-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12615957-B2 Organic electroluminescent materials and devices LBR, NR4A1, MLX HSD11B1 1920/4885HSD17B10 3805/4885MAPK1 2128/4885
US-20210280803-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR HSD11B1 2169/4885HSD17B10 3227/4885MAPK1 2446/4885
US-20240023424-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, LDLR HSD11B1 2165/4885HSD17B10 3217/4885MAPK1 2453/4885
US-10038151-B2 Organic electroluminescent materials and devices MLX, NR1H2, NR1H3 HSD11B1 1399/4885HSD17B10 2366/4885MAPK1 2335/4885
US-11043641-B2 Organic electroluminescent materials and devices LBR, MLX, MRPL38 HSD11B1 2180/4885HSD17B10 3302/4885MAPK1 2223/4885
US-20160133860-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, LBR, NR1H2 HSD11B1 1862/4885HSD17B10 3067/4885MAPK1 2288/4885
US-11832507-B2 Organic electroluminescent materials and devices MLX, LBR, LDLR HSD11B1 2165/4885HSD17B10 3217/4885MAPK1 2453/4885
US-20160133859-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MLX, NR1H2, NR1H3 HSD11B1 1399/4885HSD17B10 2366/4885MAPK1 2335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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