Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115902 | 0.83 | DPP4 (0.47) | SIGMAR1DPP4FAPPREPEPHX1 | |
| SCHEMBL13115939 | 0.81 | DPP4 (0.42) | SIGMAR1DPP4FAPPREPCHRM1 | |
| SCHEMBL23168316 | 0.80 | SMYD3 (0.45) | DPP4FAPPREPCHRM1CYP2D6 | |
| SCHEMBL12413657 | 0.78 | SIGMAR1 (0.57) | SIGMAR1EPHX1CHRM1 | |
| SCHEMBL255421 | 0.74 | EPHX1 (0.59) | GNAI3GNAO1GNAI1SIGMAR1EPHX1 | |
| SCHEMBL13115960 | 0.74 | DPP4 (0.40) | DPP4FAPPREPCHRM1CYP2D6 | |
| SCHEMBL10446115 | 0.74 | ALOX15 (0.54) | GNAI3GNAO1GNAI1SIGMAR1DPP4 | |
| SCHEMBL13115936 | 0.73 | CXCR4 (0.56) | SIGMAR1DPP4FAPPREPEPHX1 | |
| SCHEMBL13115928 | 0.73 | DPP4 (0.42) | DPP4FAPPREPRAD52CYP2D6 | |
| SCHEMBL20075929 | 0.73 | EPHX1 (0.54) | GNAI3GNAO1GNAI1EPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094912-A1 | INDOLE DERIVATIVES AS EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094912-A1 | INDOLE DERIVATIVES AS EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, ABCG2 | GNAI3 412/4885GNAO1 1747/4885GNAI1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.