Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168550 | 0.83 | USP2 (0.49) | MAPTALDH1A1NPC1TSHRRAB9A | |
| SCHEMBL23168410 | 0.81 | FPR1 (0.45) | MAPTALDH1A1LMNASMN1; SMN2HRH3 | |
| SCHEMBL23168344 | 0.79 | SMPD3 (0.40) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23168560 | 0.79 | FPR1 (0.37) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23168569 | 0.77 | GAA (0.50) | MAPTALDH1A1LMNAHRH3KDM4E | |
| SCHEMBL23168324 | 0.76 | FPR1 (0.51) | ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22650731 | 0.74 | CHRNB2 (0.35) | SMN1; SMN2KDM4EHDAC6 | |
| SCHEMBL12832973 | 0.70 | MAPT (0.57) | MAPTALDH1A1NPC1TSHRRAB9A | |
| SCHEMBL30336242 | 0.70 | MAPT (0.57) | MAPTALDH1A1NPC1TSHRRAB9A | |
| SCHEMBL19121425 | 0.69 | MAPT (0.59) | MAPTALDH1A1NPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634955-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-31 | — | — | EP | disclosed |