Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168342 | 0.74 | MAPT (0.48) | KDM4ESMN1; SMN2HDAC6 | |
| SCHEMBL24045798 | 0.74 | NPC1 (0.38) | ALOX5APFEN1 | |
| SCHEMBL24045716 | 0.73 | FAAH (0.47) | — | |
| SCHEMBL15875300 | 0.73 | FAAH (0.47) | — | |
| SCHEMBL23168410 | 0.72 | FPR1 (0.45) | KDM4ESMN1; SMN2PIK3CA | |
| SCHEMBL24045762 | 0.72 | EGLN1 (0.38) | PIM1PIM3 | |
| SCHEMBL23168409 | 0.71 | ALDH1A1 (0.53) | KDM4ESMN1; SMN2HDAC6 | |
| SCHEMBL23168569 | 0.71 | GAA (0.50) | KDM4E | |
| SCHEMBL24045705 | 0.71 | BCHE (0.38) | KDM4ESMN1; SMN2PIK3CAMTOR | |
| SCHEMBL18291708 | 0.70 | SMN1; SMN2 (0.42) | CHRNB2CHRNA4KDM4EGCKGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |