Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23169316 | 0.85 | ALDH1A1 (0.43) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL23177031 | 0.83 | LMNA (0.51) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL5913597 | 0.80 | LMNA (0.62) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL6990630 | 0.80 | LMNA (0.58) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL6597514 | 0.78 | LMNA (0.57) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL27503317 | 0.78 | VCAM1 (0.52) | LMNAMAPTRAB9AHTTALDH1A1 | |
| SCHEMBL5913106 | 0.77 | MAPT (0.64) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL22609397 | 0.77 | LMNA (0.54) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL5913543 | 0.75 | LMNA (0.56) | LMNAMAPTRAB9AHTTGAA | |
| SCHEMBL3099913 | 0.75 | SMN1; SMN2 (0.50) | LMNAMAPTRAB9AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057061-A1 | SENOLYTIC AND ANTIINFLAMMATORY PRODRUGS AND METHODS OF USE THEREOF | PEKING UNIVERSITY (CN) | 2021-04-01 | — | — | WO | disclosed |