Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23170635 | 0.81 | PNLIP (0.36) | HSPB1 | |
| SCHEMBL13857904 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL4374841 | 0.79 | HSPB1 (0.58) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL13857891 | 0.76 | NCOA1 (0.49) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL26039648 | 0.75 | HSPB1 (0.70) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL21104547 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL3563719 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL2812244 | 0.73 | MAOB (0.47) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL3024118 | 0.72 | HSPB1 (0.50) | ALDH1A1TDP1CYP3A4TSHRMAPT | |
| SCHEMBL31287801 | 0.72 | HSPB1 (0.50) | ALDH1A1TDP1CYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739090-B2 | Substituted pyrazlo[3,4-c]pyridines as selective BTK kinase inhibitors | JUMBO DRUG BANK CO., LTD. (CN) | 2023-08-29 | — | — | US | disclosed |
| US-11739090-B2 | Substituted pyrazlo[3,4-c]pyridines as selective BTK kinase inhibitors | JUMBO DRUG BANK CO., LTD. (CN) | 2023-08-29 | — | — | US | disclosed |
| WO-2021057893-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS SELECTIVE BTK KINASE INHIBITORS | 南京明德新药研发有限公司 | 2021-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739090-B2 | Substituted pyrazlo[3,4-c]pyridines as selective BTK kinase inhibitors | BTK, SYK, LCK | ALDH1A1 4115/4885TDP1 1376/4885CYP3A4 1797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.