Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HINT1 | P49773 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490509 | 0.87 | ADORA3 (0.57) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL16144340 | 0.86 | ADORA3 (0.53) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL23171189 | 0.85 | ADORA3 (0.52) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL15833376 | 0.83 | TGM2 (0.49) | NT5ESTING1PNPTGM2 | |
| SCHEMBL16144341 | 0.82 | ADORA3 (0.51) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL16374044 | 0.80 | ADORA3 (0.49) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL22475037 | 0.80 | HPGD (0.41) | ADORA3HINT1NT5ESTING1HPGD | |
| SCHEMBL20611228 | 0.80 | ADORA3 (0.52) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL15833027 | 0.80 | ADORA3 (0.49) | ADORA3HINT1NT5ESTING1PDE3B | |
| SCHEMBL15833211 | 0.79 | ADORA3 (0.48) | ADORA3HINT1NT5ESTING1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797782-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | Janssen BioPharma, Inc. (US) | 2021-03-31 | — | — | EP | disclosed |