Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23175972 | 0.89 | DGAT1 (0.48) | DGAT1GBA1HSP90AB1 | |
| SCHEMBL16840813 | 0.85 | NOTUM (0.44) | DGAT1NOTUMCYP19A1HSP90AB1 | |
| SCHEMBL14925585 | 0.84 | DGAT1 (0.43) | DGAT1NOTUMCYP19A1HSP90AB1 | |
| SCHEMBL26699501 | 0.83 | DRD2 (0.44) | DGAT1NOTUMHSP90AB1 | |
| SCHEMBL1753962 | 0.80 | GBA1 (0.45) | GBA1CYP19A1 | |
| SCHEMBL25138066 | 0.80 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL18850695 | 0.80 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL20805926 | 0.79 | NOTUM (0.43) | DGAT1NOTUMCYP19A1HSP90AB1 | |
| SCHEMBL6355508 | 0.79 | NOTUM (0.43) | DGAT1NOTUMCYP19A1HSP90AB1 | |
| SCHEMBL20805924 | 0.79 | P2RX7 (0.41) | DGAT1NOTUMCYP19A1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094950-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094950-A1 | KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE | CSNK1A1, CSNK1E, CSNK1G3 | DGAT1 1576/4885NOTUM 3592/4885GBA1 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.