Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.35 |
| ▸ | USP4 | Q13107 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936881 | 0.82 | TRPA1 (0.38) | TSHRARACHEALDH1A1USP2 | |
| SCHEMBL8763537 | 0.82 | USP2 (0.42) | TSHRALDH1A1TDP1USP2USP8 | |
| SCHEMBL9727642 | 0.79 | ALDH1A1 (0.50) | TSHRARALDH1A1USP2USP8 | |
| SCHEMBL6599639 | 0.78 | TSHR (0.43) | TSHRARACHEHAO1ALDH1A1 | |
| SCHEMBL21495996 | 0.78 | ALDH1A1 (0.40) | TSHRARALDH1A1USP2USP8 | |
| SCHEMBL28885633 | 0.77 | TSHR (0.41) | TSHRARACHEHAO1ALDH1A1 | |
| SCHEMBL16707458 | 0.73 | TSHR (0.41) | TSHRARACHEALDH1A1MAPT | |
| SCHEMBL3307820 | 0.73 | USP2 (0.37) | TSHRALDH1A1TDP1USP2USP8 | |
| SCHEMBL9751834 | 0.73 | USP2 (0.37) | TSHRALDH1A1TDP1USP2USP8 | |
| SCHEMBL10897641 | 0.73 | HAO1 (0.43) | HAO1ALDH1A1TDP1USP2USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843276-B | Multi-component composite steel slag grinding-aid excitant and preparation method thereof | 华新水泥股份有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-117843276-B | Multi-component composite steel slag grinding-aid excitant and preparation method thereof | 华新水泥股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-117843276-A | Multi-component composite steel slag grinding-aid excitant and preparation method thereof | 华新水泥股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-116355117-A | Terminal functionalized high cis-rare earth conjugated diene rubber and preparation method thereof | 青岛科技大学 | 2023-06-30 | — | — | CN | disclosed |
| EP-3252045-B1 | CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS | ABBVIE INC (US) | 2019-09-04 | — | — | EP | disclosed |
| CN-107235875-B | A method of synthesis 1,2,2- trifluoro-ethylene sulfide compound | 福州大学 | 2019-02-22 | — | — | CN | disclosed |
| EP-2867221-B1 | CYANOGUANIDINES AND THEIR SUE AS ANTIVIRAL AGENTS. | ABBVIE INC (US) | 2018-01-17 | — | — | EP | disclosed |
| EP-3252045-A1 | CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS | AbbVie Inc. (US) | 2017-12-06 | — | — | EP | disclosed |
| CN-107235875-A | A kind of method for synthesizing 1,2,2 trifluoro-ethylene sulfide compounds | 福州大学 | 2017-10-10 | — | — | CN | disclosed |
| EP-2401312-A1 | FOAM-FORMING COMPOSITIONS CONTAINING MIXTURES OF 2-CHLORO-3,3,3-TRIFLUOROPROPENE AND AT LEAST ONE HYDROFLUOROOLEFIN AND THEIR USES IN THE PREPARATION OF POLYISOCYANATE-BASED FOAMS | E. I. du Pont de Nemours and Company (US) | 2012-01-04 | — | — | EP | disclosed |
| WO-2009089400-A1 | COMPOSITIONS AND USE OF 2-CHLORO-3,3,3-TRIFLUOROPROPENE FOAM-FORMING COMPOSITION IN THE PREPARATION OF POLYISOCYANATE-BASED FOAMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-16 | — | — | WO | disclosed |
| CN-101432638-A | Plastic polarized lens | SEIKO EPSON CORP (JP) | 2009-05-13 | — | — | CN | disclosed |
| WO-2009014966-A1 | COMPOSITIONS AND USE OF TRANS-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE FOAM-FORMING COMPOSITION IN THE PREPARATION OF POLYISOCYANATE-BASED FOAMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-01-29 | — | — | WO | disclosed |
| EP-1969080-A2 | REACTIVE POLYURETHANE HOT MELT ADHESIVE | Henkel Corporation (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| WO-2007081645-A2 | REACTIVE POLYURETHANE HOT MELT ADHESIVE | HENKEL CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |
| CN-1158315-C | Process for producing ethylene/olefin interpolymers | 伊斯曼化学公司 | 2004-07-21 | — | — | CN | disclosed |
| CN-1418227-A | Procatalyst containing bidentate ligand, catalyst system and use thereof in olefin polymerization | EASTMAN CHEM CO (US) | 2003-05-14 | — | — | CN | disclosed |
| CN-1367800-A | Process for producing ethylene/olefin interpolymers | EASTMAN CHEM CO (US) | 2002-09-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076924-A1 | Piperazines as P2X7 antagonists | P2RX7, P2RX1, P2RX2 | TSHR 2283/4885AR 2520/4885ACHE 2998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.