Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765197 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2L3MBTL1TGFBR1PLGF12 | |
| SCHEMBL14865813 | 0.86 | PRKCI (0.41) | SMN1; SMN2L3MBTL1PLGF12F11 | |
| SCHEMBL31696659 | 0.83 | MGLL (0.39) | SMN1; SMN2L3MBTL1PLGF12F11 | |
| SCHEMBL23916448 | 0.79 | ENPP2 (0.33) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL454134 | 0.78 | LOXL2 (0.47) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL29526015 | 0.78 | LOXL2 (0.47) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL23916450 | 0.75 | ENPP2 (0.30) | ENPP2 | |
| SCHEMBL24023378 | 0.75 | PLCG1 (0.40) | SMN1; SMN2ENPP2KDM4EALDH1A1PRKCI | |
| SCHEMBL31197968 | 0.74 | PRKCI (0.32) | SMN1; SMN2ALDH1A1PRKCI | |
| SCHEMBL129055 | 0.74 | UHRF1 (0.48) | SMN1; SMN2L3MBTL1TGFBR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057975-A1 | MUTANT IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2021-04-01 | — | — | WO | disclosed |