Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865813 | 0.80 | PRKCI (0.41) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL23916450 | 0.80 | ENPP2 (0.30) | ENPP2 | |
| SCHEMBL30765197 | 0.79 | SMN1; SMN2 (0.36) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL23181007 | 0.79 | SMN1; SMN2 (0.36) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL31696659 | 0.77 | MGLL (0.39) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL24706908 | 0.74 | ASIC3 (0.35) | — | |
| SCHEMBL20299141 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL30001151 | 0.74 | ASIC3 (0.35) | — | |
| SCHEMBL24023378 | 0.73 | PLCG1 (0.40) | ENPP2 | |
| SCHEMBL454134 | 0.73 | LOXL2 (0.47) | PLGF12F11KLKB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | ENPP2 429/4885PLG 1875/4885F12 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.