Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HMGCR | P04035 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687238 | 0.78 | TSHR (0.54) | KDM4EALDH1A1TSHRTDP1CYP3A4 | |
| Methoxymethane SCHEMBL28666837 | 0.77 | TSHR (0.52) | KDM4EALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL13622498 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1CYP3A4MEN1 | |
| SCHEMBL2314671 | 0.76 | GRIN2D (0.64) | KDM4EALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL2316541 | 0.76 | GRIN2D (0.64) | KDM4EALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL2315188 | 0.76 | CYP1A1 (0.56) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL23996037 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL2316245 | 0.75 | APP (0.51) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2312701 | 0.75 | AMY1A (0.59) | KDM4EALDH1A1TSHRTDP1HPGD | |
| SCHEMBL27719077 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1TSHRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189306-A1 | COMPOUNDS, COMPOSITIONS AND TREATMENTS FOR V-ATPase RELATED DISEASES | KARTNER NORBERT | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189306-A1 | COMPOUNDS, COMPOSITIONS AND TREATMENTS FOR V-ATPase RELATED DISEASES | ATP6V1E1, ATP6V1G1, ATP6V1H | KDM4E 2907/4885ALDH1A1 2068/4885TSHR 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.