Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | GAA | P10253 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23996039 | 0.81 | ALDH1A1 (0.76) | KDM4EALDH1A1GAALMNAMEN1 | |
| SCHEMBL2318213 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7750362 | 0.72 | KDM4E (0.58) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL7750369 | 0.72 | KDM4E (0.58) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL13673606 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23996051 | 0.69 | RAB9A (0.58) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL28687238 | 0.69 | TSHR (0.54) | KDM4EALDH1A1GAALMNAMEN1 | |
| SCHEMBL13673599 | 0.68 | KDM4E (0.54) | KDM4EALDH1A1GAAMEN1KMT2A | |
| Methoxymethane SCHEMBL28666837 | 0.67 | TSHR (0.52) | KDM4EALDH1A1GAALMNAMEN1 | |
| SCHEMBL24211891 | 0.66 | ALDH1A1 (0.50) | KDM4EALDH1A1GAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166464-B2 | Self-assembled active agents | PCNA, POLM, MUS81 | KDM4E 3334/4885ALDH1A1 110/4885GAA 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.