SCHEMBL1954261

SCHEMBL1954261

O=c1c2ccccc2oc2cc(O)c(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.69
KDM4E B2RXH2 2/20 0.67
CYP3A4 P08684 2/20 0.67
MAPT P10636 2/20 0.67
HPGD P15428 2/20 0.67
CASP7 P55210 2/20 0.67
HSD17B10 Q99714 2/20 0.67
ALDH1A1 P00352 1/20 0.67
GLA P06280 1/20 0.67
PGAM1 P18669 1/20 0.67
CASP1 P29466 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
NPC1 O15118 3/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
GAA P10253 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
CASP3 P42574 1/20 0.59
RECQL P46063 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31512480 1.00 MAOA (0.69) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL9837311 0.86 MAOA (0.61) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL9836614 0.86 MAOA (0.61) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL9836819 0.86 MAOA (0.61) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL9836945 0.86 LMNA (0.65) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL9837713 0.86 MAOA (0.61) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL2318335 0.86 MAOA (0.66) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL3874960 0.84 AHR (0.59) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL21666688 0.84 MAOA (0.78) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL10453866 0.84 TBK1 (0.68) MAOAKDM4ECYP3A4MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2509561-B1 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING WATER SENSITIVE ACTIVES PROCTER & GAMBLE (US) 2017-08-02 EP claimed
US-9198838-B2 Porous, dissolvable solid substrate and surface resident coating comprising water sensitive actives THE PROCTER & GAMBLE COMPANY (US) 2015-12-01 US claimed
EP-2509561-A2 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING WATER SENSITIVE ACTIVES The Procter & Gamble Company (US) 2012-10-17 EP claimed
US-20110195098-A1 Porous, Dissolvable Solid Substrate and Surface Resident Coating Comprising Water Sensitive Actives THE PROCTER & GAMBLE COMPANY 2011-08-11 US claimed
WO-2011072002-A2 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING WATER SENSITIVE ACTIVES THE PROCTER & GAMBLE COMPANY (US) 2011-06-16 WO claimed
WO-2025072721-A1 COMPOSITIONS UVAGELESS LLC (US) 2025-04-03 WO disclosed
US-12018232-B2 Multilayer dissolvable solid article containing solid particles for making the same THE PROCTER & GAMBLE COMPANY (US) 2024-06-25 US disclosed
EP-2509561-B1 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING WATER SENSITIVE ACTIVES PROCTER & GAMBLE (US) 2017-08-02 EP disclosed
US-9198838-B2 Porous, dissolvable solid substrate and surface resident coating comprising water sensitive actives THE PROCTER & GAMBLE COMPANY (US) 2015-12-01 US disclosed
US-9173826-B2 Porous, dissolvable solid substrate and surface resident coating comprising a zync pyrithione THE PROCTER & GAMBLE COMPANY (US) 2015-11-03 US disclosed
EP-2536386-A1 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING A ZYNC PYRITHIONE The Procter & Gamble Company (US) 2012-12-26 EP disclosed
EP-2509561-A2 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING WATER SENSITIVE ACTIVES The Procter & Gamble Company (US) 2012-10-17 EP disclosed
EP-2509562-A2 POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING A SKIN TREATMENT ACTIVE The Gillette Company (US) 2012-10-17 EP disclosed
WO-2011103152-A1 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING A ZYNC PYRITHIONE THE PROCTER & GAMBLE COMPANY (US) 2011-08-25 WO disclosed
US-20110200649-A1 Porous, Dissolvable Solid Substrate And Surface Resident Coating Comprising A Zync Pyrithione THE PROCTER & GAMBLE COMPANY 2011-08-18 US disclosed
US-20110195098-A1 Porous, Dissolvable Solid Substrate and Surface Resident Coating Comprising Water Sensitive Actives THE PROCTER & GAMBLE COMPANY 2011-08-11 US disclosed
WO-2011072002-A2 A POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING WATER SENSITIVE ACTIVES THE PROCTER & GAMBLE COMPANY (US) 2011-06-16 WO disclosed
WO-2011071965-A2 POROUS, DISSOLVABLE SOLID SUBSTRATE AND SURFACE RESIDENT COATING COMPRISING A SKIN TREATMENT ACTIVE THE GILLETTE COMPANY (US) 2011-06-16 WO disclosed
US-20110132387-A1 Porous, Dissolvable Solid Substrate And Surface Resident Coating Comprising A Skin Treatment Active THE GILLETTE COMPANY 2011-06-09 US disclosed
US-5495005-A ANTICOAGULANTS, CARDIOVASCULAR DISORDERS NATIONAL SCIENCE COUNCIL (TW) 1996-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110132387-A1 Porous, Dissolvable Solid Substrate And Surface Resident Coating Comprising A Skin Treatment Active CUTA, DSG1, CD44 MAOA 779/4885KDM4E 352/4885CYP3A4 1711/4885
US-20110200649-A1 Porous, Dissolvable Solid Substrate And Surface Resident Coating Comprising A Zync Pyrithione PORCN, CUTA, ZYX MAOA 1432/4885KDM4E 652/4885CYP3A4 688/4885
US-20110195098-A1 Porous, Dissolvable Solid Substrate and Surface Resident Coating Comprising Water Sensitive Actives CUTA, DSG1, SPG11 MAOA 818/4885KDM4E 1583/4885CYP3A4 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.