Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 7/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339841 | 0.90 | KMT2A (0.54) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL31443033 | 0.86 | ACMSD (0.51) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL20340157 | 0.86 | ACMSD (0.51) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL23183542 | 0.79 | ACMSD (0.57) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL20339582 | 0.78 | KMT2A (0.64) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL20340172 | 0.75 | ACMSD (0.61) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL24087895 | 0.73 | ACMSD (0.45) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL32688306 | 0.73 | KMT2A (0.59) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL26847198 | 0.73 | KMT2A (0.45) | KMT2APOLBMEN1ALDH1A1HPGD | |
| SCHEMBL20339813 | 0.72 | ACMSD (0.55) | KMT2APOLBMEN1ALDH1A1ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780812-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ORSOBIO, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-20210094916-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | ORSOBIO, INC. | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094916-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | ALDH7A1, OTC, DDC | KMT2A 1374/4885POLB 757/4885MEN1 1839/4885 |
| US-11780812-B2 | Oxopyridine derivatives useful as aminocarboxymuconate semialdehyde decarboxylase (ACMSD) inhibitors | ALDH7A1, ACMSD, AMD1 | KMT2A 1309/4885POLB 906/4885MEN1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.