Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.53 |
| ▸ | CTSC | P53634 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319108 | 1.00 | PIN1 (0.53) | PIN1CTSCPKMPOLBHPGD | |
| SCHEMBL2314616 | 0.85 | PIN1 (0.59) | PIN1POLBFFAR2KDM4EMME | |
| SCHEMBL2314623 | 0.85 | PIN1 (0.59) | PIN1POLBFFAR2KDM4EMME | |
| SCHEMBL2315069 | 0.85 | PIN1 (0.59) | PIN1POLBFFAR2KDM4EMME | |
| SCHEMBL2317691 | 0.85 | FFAR2 (0.50) | PKMPOLBHPGDRAB9AFFAR2 | |
| SCHEMBL2317682 | 0.85 | FFAR2 (0.50) | PKMPOLBHPGDRAB9AFFAR2 | |
| SCHEMBL2314782 | 0.83 | HPGD (0.60) | PKMPOLBHPGDRAB9AFFAR2 | |
| SCHEMBL2314791 | 0.83 | HPGD (0.60) | PKMPOLBHPGDRAB9AFFAR2 | |
| SCHEMBL2319208 | 0.83 | MME (0.62) | PKMPOLBHPGDRAB9AFFAR2 | |
| SCHEMBL2319212 | 0.83 | MME (0.62) | PKMPOLBHPGDRAB9AFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |