SCHEMBL26568540

C[C@H](COc1ccc(C(=O)NC[C@H](c2cc3c(c(-c4ccc(F)cc4)n2)OC[C@]3(C)C(N)=O)C(F)(F)F)cc1OC1CC1)OP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	SLC5A7	Q9GZV3	8/20	0.33

▸	PDE4D	Q08499	3/20	0.33

▸	PDE4A	P27815	2/20	0.33

▸	PDE4B	Q07343	2/20	0.33

▸	PDE4C	Q08493	2/20	0.33

▸	EPHX2	P34913	2/20	0.31

▸	CYP1A2	P05177	1/20	0.30

▸	NAMPT	P43490	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25113812	0.87	SLC5A7 (0.32)	SLC5A7PDE4DPDE4APDE4BPDE4C
SCHEMBL25113809	0.87	SLC5A7 (0.32)	SLC5A7PDE4DPDE4APDE4BPDE4C
SCHEMBL23196124	0.86	NAMPT (0.33)	SLC5A7NAMPT
SCHEMBL23196125	0.85	SLC5A7 (0.32)	SLC5A7EPHX2NAMPT
SCHEMBL23195595	0.85	GABRA5 (0.31)	SLC5A7
SCHEMBL23195997	0.83	AR (0.31)	SLC5A7
SCHEMBL23196136	0.83	UGCG (0.31)	SLC5A7
SCHEMBL23196269	0.83	UGCG (0.31)	SLC5A7
SCHEMBL24987082	0.83	ALDH1A1 (0.36)	PDE4DPDE4APDE4BPDE4C
SCHEMBL25113808	0.83	PDE4A (0.34)	SLC5A7PDE4DPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023200441-A1	ANTIVIRAL HETEROCYCLIC COMPOUNDS	ENANTA PHARMACEUTICALS, INC. (US)	2023-10-19	—	—	WO	disclosed