Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 8/20 | 0.61 |
| ▸ | ALPL | P05186 | 7/20 | 0.61 |
| ▸ | GCGR | P47871 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | ALPI | P09923 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26320499 | 0.90 | RAB9A (0.56) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL18169169 | 0.79 | RAB9A (0.69) | NPC1RAB9ATDP1MAPTPOLB | |
| SCHEMBL3466913 | 0.76 | ALPG (1.00) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL23196652 | 0.75 | MAPT (0.45) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL14385406 | 0.75 | ALPG (0.55) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL23196654 | 0.74 | SMN1; SMN2 (0.44) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL12858750 | 0.73 | MAPT (0.73) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL15429998 | 0.72 | MEN1 (0.72) | ALPGALPLGCGRNPC1RAB9A | |
| SCHEMBL13856448 | 0.71 | ALPL (1.00) | ALPGALPLGCGRMAPTGAA | |
| Hydrogen Sulfide SCHEMBL23196656 | 0.71 | KMT2A (0.43) | ALPGALPLGCGRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2021-04-15 | — | — | US | disclosed |
| WO-2021067572-A2 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885ALPL 4374/4885GCGR 4625/4885 |
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885ALPL 4374/4885GCGR 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.