Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 3/20 | 0.49 |
| ▸ | ALPG | P10696 | 3/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196643 | 0.90 | ALPG (0.61) | RAB9ANPC1TDP1SMN1; SMN2MAPT | |
| SCHEMBL26320568 | 0.77 | ALPL (0.80) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| SCHEMBL26320533 | 0.77 | MAPT (0.43) | RAB9ANPC1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL18169169 | 0.76 | RAB9A (0.69) | RAB9ANPC1TDP1SMN1; SMN2MAPT | |
| SCHEMBL26320532 | 0.76 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2212904 | 0.71 | RAB9A (0.55) | RAB9ANPC1TDP1SMN1; SMN2MAPT | |
| SCHEMBL2211772 | 0.71 | GRK6 (0.56) | RAB9ANPC1TDP1SMN1; SMN2MAPT | |
| SCHEMBL1746713 | 0.69 | TSHR (0.71) | RAB9ANPC1TDP1SMN1; SMN2MAPT | |
| SCHEMBL26320508 | 0.68 | ALPG (0.48) | RAB9ANPC1TDP1SMN1; SMN2MAPT | |
| SCHEMBL1540756 | 0.67 | HTR1A (0.67) | RAB9ANPC1TDP1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | RAB9A 4097/4885NPC1 1679/4885TDP1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.