Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 16/20 | 0.47 |
| ▸ | ALPL | P05186 | 7/20 | 0.47 |
| ▸ | PLAA | Q9Y263 | 6/20 | 0.47 |
| ▸ | ALPI | P09923 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 3/20 | 0.39 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26320546 | 0.93 | ALDH1A1 (0.40) | ALPGALPLPLAAALPIGFER | |
| SCHEMBL23196644 | 0.83 | ALPG (0.47) | ALPGALPLPLAAALPIPOLB | |
| SCHEMBL23196648 | 0.76 | ALDH1A1 (0.71) | ALPGALPLPLAAALPIALDH1A1 | |
| SCHEMBL26320539 | 0.75 | ALPG (0.40) | ALPGALPLPLAAALDH1A1POLB | |
| SCHEMBL23196646 | 0.75 | ALPG (0.48) | ALPGALPLPLAAALPIGFER | |
| SCHEMBL9167178 | 0.68 | HTR1A (0.47) | — | |
| SCHEMBL26320500 | 0.68 | ALDH1A1 (0.70) | ALPGALPLALDH1A1POLBCDC25A | |
| SCHEMBL26320545 | 0.67 | ALDH1A1 (0.42) | ALPGALPLPLAAALPIGFER | |
| SCHEMBL23196647 | 0.65 | GAA (0.67) | ALPGALPLPLAAALPIALDH1A1 | |
| SCHEMBL26320872 | 0.64 | CA12 (0.47) | ALPGALPLPLAAALPIPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2023-09-21 | — | — | US | disclosed |
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | US GOV VETERANS AFFAIRS (US) | 2021-04-15 | — | — | US | disclosed |
| WO-2021067572-A2 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106567-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885ALPL 4374/4885PLAA 1855/4885 |
| US-20230293499-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO | NFKBIA, NCBP1, NFKB1 | ALPG 4545/4885ALPL 4374/4885PLAA 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.