Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197827 | 0.73 | — | — | |
| SCHEMBL2751753 | 0.70 | RAB9A (0.67) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL7865726 | 0.62 | MAPT (0.60) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL23197819 | 0.61 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL23197815 | 0.61 | LMNA (0.41) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL27699157 | 0.61 | MAPT (0.63) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL7612008 | 0.60 | KMT2A (0.60) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL6716900 | 0.60 | MAPT (0.62) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL5208634 | 0.59 | MAPT (0.70) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL23198512 | 0.59 | P2RX1 (0.40) | MAPTPOLBALOX15TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021064077-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-08 | — | — | WO | disclosed |