Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989753 | 0.85 | DRD2 (0.60) | DRD2SIGMAR1DRD3CHRM2CHRM3 | |
| SCHEMBL10370183 | 0.84 | ACHE (0.65) | DRD2SIGMAR1DRD3CHRM2CHRM3 | |
| SCHEMBL17967991 | 0.84 | DRD2 (0.58) | DRD2SIGMAR1DRD3CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL17557617 | 0.83 | DRD2 (0.57) | DRD2SIGMAR1DRD3CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL30056142 | 0.83 | DRD2 (0.57) | DRD2SIGMAR1DRD3CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL21752824 | 0.83 | DRD2 (0.57) | DRD2SIGMAR1DRD3CHRM2CHRM3 | |
| SCHEMBL27650580 | 0.81 | PRMT6 (0.58) | DRD2SIGMAR1DRD3BCL2L1ALDH1A1 | |
| SCHEMBL6310987 | 0.81 | PRMT6 (0.62) | DRD2DRD3BCL2L1ALDH1A1HPGD | |
| SCHEMBL23223705 | 0.81 | DRD2 (0.52) | DRD2SIGMAR1ALDH1A1CHRM4 | |
| SCHEMBL10370403 | 0.80 | ALDH1A1 (0.64) | DRD2DRD3BCL2L1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | claimed |