Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907119 | 0.79 | L3MBTL1 (0.53) | CCNCCDK8L3MBTL1PKMRAB9A | |
| SCHEMBL8154788 | 0.72 | ABL1 (0.49) | GPR84MAPTSMN1; SMN2 | |
| SCHEMBL7835625 | 0.72 | L3MBTL1 (0.70) | L3MBTL1RAB9AKDM4EMEN1MAPT | |
| SCHEMBL897466 | 0.72 | L3MBTL1 (0.53) | L3MBTL1PKMRAB9AKDM4EMEN1 | |
| SCHEMBL3909660 | 0.71 | L3MBTL1 (0.58) | L3MBTL1FAAHMGLLMEN1MAPT | |
| SCHEMBL2762378 | 0.71 | L3MBTL1 (0.63) | L3MBTL1RAB9AGPR84MAPTALDH1A1 | |
| SCHEMBL3711850 | 0.71 | L3MBTL1 (0.49) | CCNCCDK8L3MBTL1PKMRAB9A | |
| SCHEMBL3904040 | 0.69 | L3MBTL1 (0.50) | CCNCCDK8L3MBTL1PKMRAB9A | |
| SCHEMBL6032214 | 0.68 | L3MBTL1 (0.53) | L3MBTL1PKMRAB9AKDM4EMEN1 | |
| SCHEMBL27691514 | 0.68 | TAAR1 (0.58) | L3MBTL1RAB9ANSD2HSP90AA1G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154934-B1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND THEIR USE IN TREATING NEURODEGENERATIVE DISEASES | UNIV LILLE (FR) | 2021-04-14 | — | — | EP | claimed |