Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907119 | 0.84 | L3MBTL1 (0.53) | L3MBTL1MAPK14PKMTAAR1MAPK1 | |
| SCHEMBL3910980 | 0.77 | L3MBTL1 (0.59) | L3MBTL1PKMTAAR1NPC1RAB9A | |
| SCHEMBL9837512 | 0.76 | PBRM1 (0.54) | MAPK14PKMTAAR1MAPK1PTPN7 | |
| SCHEMBL3711850 | 0.75 | L3MBTL1 (0.49) | L3MBTL1PKMTAAR1NPC1RAB9A | |
| SCHEMBL22131082 | 0.73 | ALDH1A1 (0.38) | L3MBTL1PKMMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL381570 | 0.71 | ALDH1A1 (0.47) | MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7504935 | 0.71 | SMN1; SMN2 (0.63) | MAPK14MAPK1RAB9ACCNCCDK8 | |
| SCHEMBL11585442 | 0.70 | CA12 (0.62) | L3MBTL1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7502949 | 0.70 | NR4A2 (0.50) | MAPK14PKMRAB9ACCNCCDK8 | |
| SCHEMBL8150179 | 0.70 | MAPT (0.58) | L3MBTL1PKMMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |