Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556696 | 0.94 | CYP1A2 (0.52) | CYP1A2CYP2D6KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL562016 | 0.89 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL6400164 | 0.89 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL9854866 | 0.89 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL6401181 | 0.89 | SMN1; SMN2 (0.50) | CYP1A2CYP2D6KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6405203 | 0.82 | DPP8 (0.47) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL6398767 | 0.81 | TDP1 (0.51) | SMN1; SMN2ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL30381376 | 0.81 | DPP8 (0.45) | KDM4ESMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL5724018 | 0.81 | SMN1; SMN2 (0.51) | CYP1A2CYP2D6KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL23557949 | 0.81 | SIGMAR1 (0.43) | CYP1A2CYP2D6KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12084445-B2 | Broad-spectrum carbapenems | VenatoRx Pharmaceuticals, Inc. (US) | 2024-09-10 | — | — | US | disclosed |
| US-20210188851-A1 | BROAD-SPECTRUM CARBAPENEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-06-24 | — | — | US | disclosed |
| EP-3802538-A1 | BROAD-SPECTRUM CARBAPENEMS | Venatorx Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188851-A1 | BROAD-SPECTRUM CARBAPENEMS | MGAM, ALPI, SI | CYP1A2 2425/4885CYP2D6 798/4885KDM4E 1370/4885 |
| US-12084445-B2 | Broad-spectrum carbapenems | MGAM, ALPI, SI | CYP1A2 2425/4885CYP2D6 798/4885KDM4E 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.