Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924181 | 0.88 | PDGFRB (0.64) | PDGFRBPDGFRAPRKCETDP1L3MBTL1 | |
| SCHEMBL28010902 | 0.83 | TDP1 (0.47) | TDP1L3MBTL1SIRT5ALDH1A1KDM4E | |
| SCHEMBL378787 | 0.83 | ALDH1A1 (0.51) | PDGFRBPDGFRATDP1L3MBTL1SIRT5 | |
| SCHEMBL15882797 | 0.82 | PDGFRB (0.55) | PDGFRBPDGFRATDP1L3MBTL1SIRT5 | |
| SCHEMBL31634147 | 0.81 | SIRT5 (0.47) | TDP1L3MBTL1SIRT5ALDH1A1KDM4E | |
| SCHEMBL34462112 | 0.80 | TDP1 (0.44) | TDP1L3MBTL1SIRT5ALDH1A1KDM4E | |
| SCHEMBL31482564 | 0.80 | TDP1 (0.44) | TDP1L3MBTL1SIRT5ALDH1A1KDM4E | |
| SCHEMBL28010903 | 0.79 | CYP1A2 (0.47) | TDP1L3MBTL1SIRT5ALDH1A1KDM4E | |
| SCHEMBL15882772 | 0.78 | PDGFRB (0.49) | PDGFRBPDGFRATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL27497870 | 0.78 | MAPT (0.50) | PDGFRBPDGFRATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |