Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23199801 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2MTNR1A | |
| SCHEMBL24177770 | 0.90 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2MTNR1A | |
| Hydrochloric Acid SCHEMBL23199832 | 0.86 | POLB (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL24177750 | 0.81 | CYP1A2 (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL30846897 | 0.80 | CYP1A2 (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2MTNR1A | |
| SCHEMBL24177783 | 0.80 | KMT2A (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL27290057 | 0.76 | HSD17B10 (0.57) | ALDH1A1KDM4EMAPTLMNAKMT2A | |
| SCHEMBL378787 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2MTNR1ALMNA | |
| SCHEMBL28010902 | 0.76 | TDP1 (0.47) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL27903563 | 0.75 | KMT2A (0.65) | ALDH1A1MAPTSMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |