Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200084 | 0.73 | HPGD (0.58) | ALDH1A1MAPTNPSR1HPGDKMT2A | |
| SCHEMBL4981629 | 0.69 | DRD4 (0.44) | ALDH1A1MAPTHPGDKMT2AEPHX1 | |
| SCHEMBL433273 | 0.64 | OPRL1 (0.59) | OPRL1KMT2A | |
| SCHEMBL25836749 | 0.62 | RAB9A (0.53) | ALDH1A1MAPTHPGDKMT2AEPHX1 | |
| SCHEMBL24632523 | 0.62 | NPC1 (0.42) | OPRL1TRPV1ALDH1A1KMT2AEPHX1 | |
| SCHEMBL18415480 | 0.61 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL27171506 | 0.61 | OPRL1 (0.54) | OPRL1 | |
| SCHEMBL14465083 | 0.61 | S1PR2 (0.51) | ALDH1A1MAPTNPSR1HPGDKMT2A | |
| SCHEMBL25836962 | 0.61 | HPGD (0.46) | ALDH1A1MAPTHPGDKMT2AEPHX1 | |
| SCHEMBL17731192 | 0.61 | OPRL1 (0.50) | OPRL1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802503-A1 | UREA DERIVATIVE MODULATORS OF TRYPTOPHAN CATABOLISM | E-Therapeutics plc (GB) | 2021-04-14 | — | — | EP | disclosed |