Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 16/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MPEG1 | Q2M385 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200905 | 0.84 | HKDC1 (0.50) | HKDC1IDO1CDC25ACDC25BALOX5 | |
| SCHEMBL5163654 | 0.74 | HKDC1 (0.69) | HKDC1IDO1CDC25ACDC25BALOX5 | |
| SCHEMBL9655387 | 0.73 | ALOX5 (0.67) | ALOX5MPEG1 | |
| SCHEMBL4463980 | 0.72 | HKDC1 (0.67) | HKDC1IDO1CDC25ACDC25BALOX5 | |
| SCHEMBL5983372 | 0.71 | HKDC1 (0.72) | HKDC1IDO1CDC25ACDC25BALOX5 | |
| SCHEMBL9654553 | 0.68 | HKDC1 (0.67) | HKDC1IDO1CDC25ACDC25BALOX5 | |
| SCHEMBL5820458 | 0.67 | MAPT (0.53) | HKDC1IDO1CDC25ACDC25BKDM4E | |
| SCHEMBL9578693 | 0.67 | ALOX5 (0.67) | HKDC1IDO1CDC25ACDC25BALOX5 | |
| SCHEMBL30004035 | 0.67 | MAPT (0.53) | HKDC1IDO1CDC25ACDC25BKDM4E | |
| SCHEMBL3417111 | 0.66 | HKDC1 (0.56) | HKDC1IDO1CDC25ACDC25BALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214303-A1 | SCORPION VENOM BENZOQUINONE DERIVATIVES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-07-15 | — | — | US | disclosed |
| US-20210214303-A1 | SCORPION VENOM BENZOQUINONE DERIVATIVES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-07-15 | — | — | US | disclosed |
| US-20210214303-A1 | SCORPION VENOM BENZOQUINONE DERIVATIVES AND USES THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-07-15 | — | — | US | disclosed |
| EP-3801765-A1 | SCORPION VENOM BENZOQUINONE DERIVATIVES AND USES THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-3801765-A1 | SCORPION VENOM BENZOQUINONE DERIVATIVES AND USES THEREOF | The Board of Trustees of the Leland Stanford Junior University (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-112512635-A | Scorpion venom benzoquinone derivative and its use | 斯坦福大学校董事会 | 2021-03-16 | — | — | CN | disclosed |
| CN-112512635-A | Scorpion venom benzoquinone derivative and its use | 斯坦福大学校董事会 | 2021-03-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214303-A1 | SCORPION VENOM BENZOQUINONE DERIVATIVES AND USES THEREOF | MC1R, MRM1, MB | HKDC1 3463/4885IDO1 689/4885CDC25A 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.