Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30514361 | 1.00 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL27976009 | 0.85 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL1010387 | 0.85 | CYP1A2 (0.73) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL5151529 | 0.85 | PDE4A (0.71) | CYP1A2CYP3A4TSHRGAAPOLB | |
| SCHEMBL10316407 | 0.85 | FYN (0.60) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL1493250 | 0.84 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL10316380 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL12560338 | 0.84 | ERN1 (0.63) | CYP1A2CYP3A4POLBPDE4APDE4B | |
| SCHEMBL1333620 | 0.83 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL430038 | 0.83 | TUBB4A (0.59) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043594-B2 | Biphenyl derivative compound and use thereof | EWHA University—Industry Collaboration Foundation (KR) | 2024-07-23 | — | — | US | disclosed |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-08 | — | — | US | disclosed |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-08 | — | — | US | disclosed |
| EP-3805193-A1 | NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF | Ewha University-Industry Collaboration Foundation (KR) | 2021-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043594-B2 | Biphenyl derivative compound and use thereof | NME4, PCK2, DNAJA3 | CYP1A2 3588/4885CYP3A4 2994/4885CYP2C19 1891/4885 |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | NME4, PCK2, DNAJA3 | CYP1A2 3571/4885CYP3A4 3056/4885CYP2C19 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.