Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | MC2R | Q01718 | 1/20 | 0.46 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753370 | 0.83 | CNR2 (0.49) | DGAT2CNR2CNR1PBKMEN1 | |
| SCHEMBL31077928 | 0.82 | DGAT2 (0.49) | DGAT2ALDH1A1MC2RPBKACP1 | |
| SCHEMBL31077879 | 0.82 | MC2R (0.58) | DGAT2MC2RACP1 | |
| SCHEMBL28598280 | 0.80 | USP2 (0.58) | DGAT2ALDH1A1MEN1KMT2A | |
| SCHEMBL28598281 | 0.80 | USP2 (0.58) | DGAT2ALDH1A1MEN1KMT2A | |
| SCHEMBL10107496 | 0.76 | CNR2 (0.54) | DGAT2ALDH1A1CNR2CNR1MEN1 | |
| SCHEMBL1753334 | 0.73 | CNR2 (0.55) | ALDH1A1CNR2CNR1MEN1KMT2A | |
| SCHEMBL23201615 | 0.72 | L3MBTL1 (0.52) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL10107630 | 0.71 | CNR2 (0.51) | DGAT2ALDH1A1CNR2CNR1 | |
| SCHEMBL1753490 | 0.71 | DRD4 (0.55) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | claimed |