SCHEMBL23201898

SCHEMBL23201898

COC(=O)[C@@H](N)Cc1ccc(OC)cc1OC

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.51
DPP7 Q9UHL4 1/20 0.49
ALDH1A1 P00352 2/20 0.48
HTR2A P28223 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
POLB P06746 1/20 0.46
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23201900 1.00 APLNR (0.51) APLNRDPP7ALDH1A1HTR2AMEN1
SCHEMBL28622709 0.89 ALDH1A1 (0.49) APLNRDPP7ALDH1A1HTR2AMEN1
SCHEMBL29519833 0.87 HSD17B10 (0.49) APLNRDPP7ALDH1A1HTR2AMEN1
SCHEMBL20397701 0.85 MEN1 (0.43) DPP7ALDH1A1HTR2AMEN1KMT2A
Hydrochloric Acid SCHEMBL8862614 0.85 HSD17B10 (0.48) APLNRDPP7HTR2AMEN1KMT2A
SCHEMBL31725864 0.85 ALDH1A1 (0.41) APLNRDPP7ALDH1A1MEN1KMT2A
SCHEMBL24981985 0.84 ALDH1A1 (0.47) ALDH1A1HTR2AMEN1KMT2A
SCHEMBL28989317 0.84 ALDH1A1 (0.47) ALDH1A1HTR2AMEN1KMT2A
SCHEMBL20397868 0.84 KIF11 (0.43) ALDH1A1POLB
SCHEMBL27665685 0.80 MEN1 (0.52) APLNRDPP7HTR2AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805237-B1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND JIANGSU CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) 2026-01-28 EP disclosed
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2023-01-03 US disclosed
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2023-01-03 US disclosed
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2021-07-15 US disclosed
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF JIANGSU CHIA TAI FENGHAI PHARMACEUTICAL CO., LTD. (CN) 2021-07-15 US disclosed
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214377-A1 SYNTHESIS OF PEPTIDE BORATE ESTER COMPOUND AND USE THEREOF SEM1, VIP, PSMB11 APLNR 2578/4885DPP7 235/4885ALDH1A1 4592/4885
US-11542283-B2 Synthesis of peptide borate ester compound and use thereof SEM1, VIP, PSMB11 APLNR 2578/4885DPP7 235/4885ALDH1A1 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.