Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912461 | 0.84 | GABRP (0.47) | VNN1MAP4K4 | |
| SCHEMBL30445761 | 0.82 | NNMT (0.44) | NNMTSMN1; SMN2HPGDSVNN1CYP11B2 | |
| SCHEMBL1828070 | 0.82 | NNMT (0.44) | NNMTSMN1; SMN2HPGDSVNN1CYP11B2 | |
| SCHEMBL28509281 | 0.80 | NNMT (0.47) | NNMTSMN1; SMN2CHEK2HPGDSMKNK1 | |
| SCHEMBL23167323 | 0.79 | HDAC6 (0.59) | — | |
| SCHEMBL2087026 | 0.79 | NNMT (0.50) | NNMTSMN1; SMN2CHEK2HPGDSMKNK1 | |
| SCHEMBL26337535 | 0.78 | LMNA (0.42) | NNMTSMN1; SMN2HPGDSVNN1CYP11B2 | |
| SCHEMBL20601801 | 0.78 | PDGFRB (0.48) | PSMD14 | |
| SCHEMBL12350329 | 0.77 | NNMT (0.40) | NNMTSMN1; SMN2HPGDSVNN1CYP11B2 | |
| Hydrochloric Acid SCHEMBL23167395 | 0.77 | PDGFRB (0.47) | PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067859-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | TENAYA THERAPEUTICS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |