Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950643 | 0.87 | OPRL1 (0.49) | OPRL1OPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL14947619 | 0.78 | GPR119 (0.46) | OPRL1OPRM1 | |
| SCHEMBL23207727 | 0.77 | OPRM1 (0.56) | OPRL1OPRM1SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL2583472 | 0.75 | OPRL1 (0.38) | OPRL1OPRM1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL26947589 | 0.75 | SLC6A4 (0.51) | OPRL1OPRM1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14950658 | 0.71 | OPRL1 (0.40) | OPRL1OPRM1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5718925 | 0.71 | OPRL1 (0.72) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL6491624 | 0.71 | ALDH1A1 (0.62) | OPRL1OPRM1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6491621 | 0.71 | ALDH1A1 (0.62) | OPRL1OPRM1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14950683 | 0.70 | PKLR (0.44) | OPRL1OPRM1OPRD1OPRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235937-A1 | TREATMENT OF ANTIDEPRESSANT RESISTANT SUBJECTS | Actinogen Medical Limited (AU) | 2023-12-14 | — | — | WO | disclosed |
| WO-2021062472-A1 | MEDICINAL COGNITIVE TREATMENTS | Actinogen Medical Limited (AU) | 2021-04-08 | — | — | WO | disclosed |