Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396664 | 0.85 | ADRB1 (0.71) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL2325937 | 0.81 | SMN1; SMN2 (0.56) | KDM4EALDH1A1LMNA | |
| SCHEMBL2321072 | 0.79 | DRD4 (0.49) | ALDH1A1HTR1ADRD2DRD3ADRA1B | |
| SCHEMBL3236477 | 0.77 | DRD2 (0.65) | ADRB1ALDH1A1AKR1C3LMNAHTR1A | |
| SCHEMBL30407939 | 0.76 | ADRB1 (0.65) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL1825806 | 0.76 | ADRB1 (0.65) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL2323800 | 0.76 | ADRB1 (0.55) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL2096393 | 0.75 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL11216112 | 0.75 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL424507 | 0.75 | DRD2 (0.75) | ADRB1KDM4EALDH1A1PLA2G1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |