Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | GSK3A | P49840 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | LDHB | P07195 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559940 | 0.85 | KDM4E (0.53) | KDM4EMAPTHSD17B10HPGDGSK3A | |
| SCHEMBL2559939 | 0.85 | KDM4E (0.53) | KDM4EMAPTHSD17B10HPGDGSK3A | |
| SCHEMBL5737282 | 0.85 | KDM4E (0.56) | KDM4EMAPTHSD17B10HPGDGSK3A | |
| SCHEMBL1806482 | 0.85 | ALDH1A1 (0.57) | KDM4EMAPTHPGDGSK3AGSK3B | |
| SCHEMBL2319080 | 0.81 | KDM4E (0.60) | KDM4EMAPTHSD17B10HPGDGSK3A | |
| SCHEMBL1116276 | 0.80 | HTRA2 (0.56) | KDM4EMAPTHPGDALDH1A1POLB | |
| SCHEMBL31358754 | 0.78 | LDHA (0.56) | KDM4EMAPTHSD17B10HPGDALDH1A1 | |
| SCHEMBL2760413 | 0.78 | KDM4E (0.61) | KDM4EMAPTHSD17B10HPGDGSK3A | |
| SCHEMBL7833840 | 0.77 | ALDH1A1 (0.51) | KDM4EMAPTHPGDGSK3AGSK3B | |
| SCHEMBL4704691 | 0.77 | LDHA (0.64) | KDM4EMAPTHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |