Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.34 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619685 | 0.92 | L3MBTL1 (0.46) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL23210028 | 0.92 | L3MBTL1 (0.46) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL29619701 | 0.91 | SLC6A9 (0.42) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL23209843 | 0.91 | SLC6A9 (0.42) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL23210176 | 0.80 | SLC6A9 (0.45) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL29619704 | 0.80 | SLC6A9 (0.45) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL23212925 | 0.78 | SLC6A9 (0.43) | L3MBTL1SLC6A9SLC6A5PTGER1LMNA | |
| SCHEMBL29619700 | 0.77 | SGMS2 (0.48) | L3MBTL1LMNAMAPTLIPE | |
| SCHEMBL23210255 | 0.77 | SGMS2 (0.48) | L3MBTL1LMNAMAPTLIPE | |
| SCHEMBL23295193 | 0.76 | MRGPRX4 (0.41) | L3MBTL1PTGER1LMNAKDM1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070090-A1 | 2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS | NOVARTIS AG (CH) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021070091-A1 | 5-OXA-2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS | NOVARTIS AG (CH) | 2021-04-15 | — | — | WO | disclosed |