Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314265 | 0.92 | GRM4 (0.33) | — | |
| SCHEMBL4398650 | 0.91 | GUCY1B2 (0.35) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1KMT2A | |
| SCHEMBL13519606 | 0.89 | KMT2A (0.39) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1KMT2A | |
| SCHEMBL2319128 | 0.89 | KMT2A (0.39) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1KMT2A | |
| SCHEMBL2321394 | 0.88 | PTGIR (0.31) | — | |
| SCHEMBL2316451 | 0.86 | SRD5A2 (0.30) | — | |
| SCHEMBL2313919 | 0.86 | SIGMAR1 (0.33) | KMT2A | |
| SCHEMBL2319013 | 0.86 | LTA4H (0.32) | — | |
| SCHEMBL2318163 | 0.85 | DRD2 (0.36) | KMT2A | |
| SCHEMBL2317120 | 0.85 | MCHR1 (0.34) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | claimed |